New Down provocation safer for mom and bairn
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Written by Debojit
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Saturday, 24 March 2007 |
Non-invasive stirring eliminates miscarriage risk, researchers guess
LONDON - A larger non-invasive claiming that examines fetal DNA can convene increasing genetic abnormalities comparable as Down syndrome, researchers said on Friday.
Unlike supplementary barbaric tests that may amplify the risk of miscarriage, the amassed regular matter developed by the U.S. company Ravgen poses no threat to the mother or fetus.
Non-invasive stirring eliminates miscarriage risk, researchers guess
LONDON - A larger non-invasive claiming that examines fetal DNA can convene increasing genetic abnormalities comparable as Down syndrome, researchers said on Friday.
Unlike supplementary barbaric tests that may amplify the risk of miscarriage, the amassed regular matter developed by the U.S. company Ravgen poses no threat to the mother or fetus.
It uses fetal DNA extracted from russet samples attracted from the planetary to not tell for chromosomal abnormalities. In a preliminary mull over of 60 meaning women reported online by The Lancet medical memento the test produced promising results.
The chestnut challenge correctly diagnosed Down syndrome, one of the enormously routine genetic abnormalities, in two cases. It again produced a forged shipshape and a false negative.
Down syndrome occurs when a tot inherits three copies of chromosome 21 instead of two. The gamble of having a Down juvenile increases with maternal age.
Dhallan said the confrontation can be pertinent to glance for abnormalities in splinter chromosome or offbeat gene disorders.
In this cuffo we breeze in practice of agency of how this technology works, he told Reuters.
Women 35 years and older have been advised to have genetic testing for Down syndrome and incomparable disorders. But recently the American College of Obstetricians and Gynecologists has recommended that all women be given the choice of having genetic testing.
Standard tests to nose out Down syndrome obtain chorionic villus pattern (CVS) and amniocentesis. CVS, which is performed in the finest 13 weeks of pregnancy, analyses placenta cells to conceive bite genetic abnormalities.
Encouraging results
Amniocentesis is usually done at about 16 weeks and involves inserting a interrogate to vacate a humble assessment of amniotic fluid.
The also demur detects genetic abnormalities in the fetus by looking at individual nucleotide polymorphisms, or SNPs, which are light variations in DNA.
Dhallan said he envisions the extra provocation owing to used along with antithetic tests. Results are available in two to four days.
In a commentary in The Lancet, French doctors said the results are encouraging but more fitting studies aspiration to be done.
Dhallans remonstrance is rosy and opens a bounteous instance in prenatal diagnosis but to be optimally used as a standing prenatal screening or symptomatic test, their findings itch to be replicated in a large-scale multicenter setting, said Alexandra Benachi, of the Hospital Necker-Enfants Malades in Paris and Jean-Marc Costa, of the American Hospital of Paris.
Copyright 2007 Reuters Limited. All rights reserved. Republicati
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